Chargers at 49ers: 48–19
ChargersSD4–1
Week 6 October 15, 2006
4819
Final
49ersSF2–4
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| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Buffalo Bills | 6–1 | .857 | +52 |
 NE Patriots | 5–3 | .625 | +22 |
 NY Jets | 2–6 | .250 | -18 |
 Miami Dolphins | 1–6 | .143 | -64 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Pittsburgh Steelers | 6–2 | .750 | +36 |
 Cincinnati Bengals | 5–2 | .714 | +48 |
 Cleveland Browns | 5–3 | .625 | -34 |
 Baltimore Ravens | 4–4 | .500 | -24 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 JAX Jaguars | 5–2 | .714 | +85 |
 Houston Texans | 2–5 | .286 | -5 |
 Indianapolis Colts | 2–6 | .250 | -61 |
 Tennessee Titans | 1–7 | .125 | -55 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Denver Broncos | 6–2 | .750 | +7 |
 Kansas City Chiefs | 5–2 | .714 | +36 |
 Las Vegas Raiders | 4–4 | .500 | -9 |
| LA Chargers | 0–7 | .000 | -76 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 NY Giants | 4–2–1 | .643 | +2 |
 Dallas Cowboys | 3–5 | .375 | +6 |
 WAS Commanders | 2–4–1 | .357 | -23 |
 Philadelphia Eagles | 2–6 | .250 | -65 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Minnesota Vikings | 6–1 | .857 | +47 |
 Chicago Bears | 6–2 | .750 | +54 |
 Detroit Lions | 5–2 | .714 | +23 |
 GB Packers | 5–3 | .625 | +7 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
 Carolina Panthers | 3–4 | .429 | -15 |
 TB Buccaneers | 3–5 | .375 | +27 |
 Atlanta Falcons | 3–5 | .375 | -18 |
 NO Saints | 2–5 | .286 | -32 |
| Team | W–L–T | PCT | DIFF |
|---|---|---|---|
| SF 49ers | 6–1 | .857 | +58 |
 LA Rams | 4–4 | .500 | +26 |
 Seattle Seahawks | 4–4 | .500 | +26 |
 Arizona Cardinals | 3–5 | .375 | -63 |